The Center for AI for Social Science addresses the gap in current AI research that emphasizes "technical optimization while neglecting social context". It aims to transform research paradigms toward a multidimensional social intelligence framework that integrates "value alignment, social embedding, and cultural adaptation". The Center establishes a research framework consisting of three key components:

1. A value-guidance mechanism grounded in normative ethics to establish an AI moral decision-making framework.
2. A computational social science model integrating complex systems theory, focusing on digital representations of social systems, including digital governance simulation, multi-scale modeling, and social sensing.
3. A cognitive computing framework incorporating cultural anthropology to study cultural semantic representation, adaptation mechanisms, and cultural diffusion modeling. Leveraging the strengths of the Guangdong-Hong Kong-Macao Greater Bay Area, the Center builds a triadic innovation system integrating ethical governance, social computation, and cultural cognition, providing technological support and demonstrative practices for national AI governance and global engagement.